Price Checker / CPT 45380
How much does Colonoscopy with biopsy cost?
CPT 45380 · Based on 2026 Medicare rates and hospital-published pricing
The average hospital charge is about 3x the fair price. You have grounds to ask for a reduction.
Fair price
$1,950–$2,300
What this should cost
With insurance
~$2,500
Typical out-of-pocket
Overcharged if over
$2,900
Push back above this
The average hospital charge of $6,416 is $4,266 over the fair price (about 3x the fair rate).
What hospitals charge for Colonoscopy with biopsy
From hospital-published transparency (MRF) files. These are the hospitals in our database that list this procedure.
| Hospital | Gross Charge | Cash Rate | vs Medicare |
|---|---|---|---|
| Stony Brook Eastern Long Island Hospital , NY | $2,290 | — | 15742% |
| Pacifica Hospital of the Valley Sun Valley, CA | $61,772 | — | 12770% |
| Down East Community Hospital Machias, ME | $18,211 | — | 3372% |
| Georgetown Community Hospital GEORGETOWN, KY | $12,158 | — | 2433% |
| Los Alamos Medical Center LOS ALAMOS, NY | $11,418 | — | 2279% |
| West Holt Memorial Hospital Atkinson, NE | $10,132 | — | 1927% |
| Wythe County Community Hospital WYTHEVILLE, VA | $9,604 | — | 1901% |
| Brodstone Memorial Hospital Superior, NE | $8,634 | — | 1663% |
| Community Medical Center Falls City, NE | $8,626 | — | 1643% |
| Bourbon Community Hospital PARIS, KY | $8,239 | — | 1617% |
| Brown County Hospital Ainsworth, NE | $4,048 | — | 1587% |
| Meadowview Regional Medical Center MAYSVILLE, KY | $7,246 | — | 1410% |
| Cornerstone Specialty Hospitals Austin Austin, TX | $6,432 | — | 1240% |
| Cornerstone Specialty Hospitals Bossier City Bossier City, LA | $6,432 | — | 1240% |
| Cornerstone Specialty Hospitals Huntington Huntington, WV | $6,432 | — | 1240% |
Were you billed for this procedure?
Send us your bill and we'll compare every line item against Medicare rates and your hospital's published prices. Free review, no obligation.
About Colonoscopy with biopsy
CPT code 45380 refers to colonoscopy with biopsy (billing description: "Colonoscopy and biopsy"). Under the 2026 Medicare Physician Fee Schedule, it is reimbursed at $178 in a facility (hospital or surgery center) and $480 in a doctor's office.
The Medicare rate is the closest thing to an objective "what this work is actually worth." A fair cash price for the uninsured is generally 1.5–3x that rate. Hospital sticker (gross) charges are often far higher — but almost nobody actually pays them.
What to do if you were overcharged
- 1Send us your bill — we'll identify this code and compare it against the rates shown above.
- 2Get a dispute letter — citing the Medicare rate and your hospital's own published pricing data.
- 3We negotiate for you — 25% of savings, no savings = no fee.