Price Checker / CPT 88319
How much does Enzyme Histochemistry cost?
CPT 88319 · Based on 2026 Medicare rates and hospital-published pricing
The average hospital charge is around 9.9x the fair price — among the most extreme markups. Dispute this.
Fair price
$550–$640
What this should cost
With insurance
~$1,400
Typical out-of-pocket
Overcharged if over
$800
Push back above this
The average hospital charge of $5,930 is $5,330 over the fair price (about 9.9x the fair rate).
What hospitals charge for Enzyme Histochemistry
From hospital-published transparency (MRF) files. These are the hospitals in our database that list this procedure.
| Hospital | Gross Charge | Cash Rate | vs Medicare |
|---|---|---|---|
| Novant Health Pender Medical Center , NC | $10,394 | — | 7542% |
| SGMC Health Lanier Campus LAKELAND, GA | $1,465 | — | 744% |
Were you billed for this procedure?
Send us your bill and we'll compare every line item against Medicare rates and your hospital's published prices. Free review, no obligation.
About Enzyme Histochemistry
CPT code 88319 refers to enzyme histochemistry (billing description: "Enzyme histochemistry"). Under the 2026 Medicare Physician Fee Schedule, it is reimbursed at $132 in a facility (hospital or surgery center) and $132 in a doctor's office.
The Medicare rate is the closest thing to an objective "what this work is actually worth." A fair cash price for the uninsured is generally 1.5–3x that rate. Hospital sticker (gross) charges are often far higher — but almost nobody actually pays them.
What to do if you were overcharged
- 1Send us your bill — we'll identify this code and compare it against the rates shown above.
- 2Get a dispute letter — citing the Medicare rate and your hospital's own published pricing data.
- 3We negotiate for you — 25% of savings, no savings = no fee.